Richard H. J. Begent: search on Z-Library

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1

Production of recombinant protein in Pichia pastoris by fermentation

Tolner, Berend, Smith, Lisa, Begent, Richard H J, Chester, Kerry A

Journal:

Nature Protocols

Year:

2006

Language:

english

File:

PDF, 333 KB

english, 2006

2

Antibody-directed enzyme prodrug therapy (ADEPT) for cancer

Bagshawe, Kenneth D, Sharma, Surinder K, Begent, Richard HJ

Journal:

Expert Opinion on Biological Therapy

Year:

2004

Language:

english

File:

PDF, 184 KB

english, 2004

3

Reversible Dimer Formation and Stability of the Anti-tumour Single-chain Fv Antibody MFE-23 by Neutron Scattering, Analytical Ultracentrifugation, and NMR and FT-IR Spectroscopy

Yie Chia Lee, Mark K. Boehm, Kerry A. Chester, Richard H.J. Begent, Stephen J. Perkins

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 698 KB

english, 2002

4

Catalytic activity of an in vivo tumor targeted anti-CEA scFv::carboxypeptidase G2 fusion protein

Jeetendra Bhatia, Surinder K. Sharma, Kerry A. Chester, R. Barbara Pedley, Robert W. Boden, David A. Read, Geoffery M. Boxer, N. Paul Michael, Richard H. J. Begent

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

5

IBC’s 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics International Conferences and the 2012 Annual Meeting of The Antibody Society

Klöhn, Peter-Christian, Wuellner, Ulrich, Zizlsperger, Nora, Zhou, Yu, Tavares, Daniel, Berger, Sven, Zettlitz, Kirstin A., Proetzel, Gabriele, Yong, May, Begent, Richard H.J., Reichert, Janice M

Journal:

Year:

2013

Language:

english

File:

PDF, 582 KB

english, 2013

6

Erratum to: Monoclonal Antibody Administration

Richard Henry,John Begent,Rosamund Barbara Pedley

Journal:

Clinical Pharmacokinetics

Year:

1992

Language:

english

File:

PDF, 164 KB

english, 1992

7

Crystal structure of the anti-(carcinoembryonic antigen) single-chain Fv antibody MFE-23 and a model for antigen binding based on intermolecular contacts

BOEHM, Mark K., CORPER, Adam L., WAN, Tommy, SOHI, Maninder K., SUTTON, Brian J., THORNTON, Jeremy D., KEEP, Patricia A., CHESTER, Kerry A., BEGENT, Richard H. J., PERKINS, Stephen J.

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 353 KB

english, 2000

8

The effect of radiosensitizers on radio-immunotherapy, using 131I-Labelled anti-cea antibodies in a human colonic xenograft model

R. Barbara Pedley, Richard H. J. Begent, Joan A. Boden, Robert Boden, Theresa Adam, Kenneth D. Bagshawe

Journal:

International Journal of Cancer

Year:

1991

Language:

english

File:

PDF, 683 KB

english, 1991

9

Antibody-directed enzyme prodrug therapy: pharmacokinetics and plasma levels of prodrug and drug in a phase I clinical trial

Janet Martin, Stephen M. Stribbling, Grace K. Poon, Richard H. J. Begent, Mark Napier, Surinder K. Sharma, C. J. Springer

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 370 KB

english, 1997

10

Engineering Antibodies for Clinical Applications in Cancer

Chester, Kerry, Pedley, Barbara, Tolner, Berend, Violet, John, Mayer, Astrid, Sharma, Surinder, Boxer, Geoff, Green, Alan, Nagl, Sylvia, Begent, Richard

Journal:

Year:

2004

Language:

english

File:

PDF, 151 KB

english, 2004

11

EMOP/CA chemotherapy for the treatment of aggressive non-Hodgkin's lymphomas

Glaser, Mark G., Bagshawe, Kenneth D., Smith, David B., Ledermann, Jonathan A., Boesen, Evelyn, Newlands, Edward S., Begent, Richard H.J., Rustin, Gordon J.S.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1989

Language:

english

File:

PDF, 364 KB

english, 1989

12

Incentivizing standards development and adoption

Reddington, Fiona, Wilkinson, J Max, Clark, Robin, Begent, Richard H

Journal:

Nature Biotechnology

Year:

2007

Language:

english

File:

PDF, 80 KB

english, 2007

13

Recent advances in tumour imaging use of radiolabelled antitumour antibodies

Richard H.J. Begent

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1984

Language:

english

File:

PDF, 1.65 MB

english, 1984

14

Oncology Information Exchange opens up databases

Journal:

The Lancet Oncology

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

15

Monoclonal Antibody Administration

Richard Henry,John Begent,Dr Rosamund Barbara Pedley

Journal:

Clinical Pharmacokinetics

Year:

1992

Language:

english

File:

PDF, 535 KB

english, 1992

16

Synthesis and biological evaluation of novel pyrrolo[2,1-c][1,4]benzodiazepine prodrugs for use in antibody-directed enzyme prodrug therapy

Luke A. Masterson, Victoria J. Spanswick, John A. Hartley, Richard H. Begent, Philip W. Howard, David E. Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 133 KB

english, 2006

17

Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice

Ethaar El-Emir, Geoffrey M. Boxer, Ingrid A. Petrie, Robert W. Boden, Jason L.J. Dearling, Richard H.J. Begent, R. Barbara Pedley

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 1.57 MB

english, 2005

18

Identification of a human ribosomal protein mRNA with increased expression in colorectal tumours

Kerry A. Chester, Lynda Robson, Richard H.J. Begent, Ian C. Talbot, James H. Pringle, Lindsey Primrose, Andrew J.S. Macpherson, Geoff Boxer, Peter Southall, Alan D.B. Malcolm

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1989

Language:

english

File:

PDF, 974 KB

english, 1989

19

Establishing a knowledge trail from molecular experiments to clinical trials

May Yee Yong, Alejandra González-Beltrán, Richard Begent

Journal:

New Biotechnology

Year:

2011

Language:

english

File:

PDF, 1.88 MB

english, 2011

20

Nonuniform Absorbed Dose Distribution in the Kidney: The Influence of Organ Architecture

Green, Alan, Flynn, Aiden, Pedley, R. Barbara, Dearling, Jason, Begent, Richard

Journal:

Cancer Biotherapy & Radiopharmaceuticals

Year:

2004

Language:

english

File:

PDF, 805 KB

english, 2004

21

The Nonuniformity of Antibody Distribution in the Kidney and its Influence on Dosimetry

Flynn, Aiden A., Pedley, R. Barbara, Green, Alan J., Dearling, Jason L., El-Emir, Ethaar, Boxer, Geoffrey M., Boden, Robert, Begent, Richard H. J.

Journal:

Radiation Research

Year:

2003

Language:

english

File:

PDF, 527 KB

english, 2003

22

Antibody directed enzyme prodrug therapy - making a complex system work in practice

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 23 KB

english, 2001

23

A model-based approach for the optimization of radioimmunotherapy through antibody design and radionuclide selection

Aiden A. Flynn, Alan J. Green, R. Barbara Pedley, Geoffrey M. Boxer, Jason Dearling, Rebecca Watson, Robert Boden, Richard H. J. Begent

Journal:

Year:

2002

Language:

english

File:

PDF, 2.00 MB

english, 2002

24

Gestational and nongestational trophoblastic tumors distinguished by DNA analysis

Rosemary A. Fisher, Edward S. Newlands, Alec J. Jeffreys, Geoffrey M. Boxer, Richard H. J. Begent, Gordon J. S. Rustin, Kenneth D. Bagshawe

Journal:

Year:

1992

Language:

english

File:

PDF, 607 KB

english, 1992

25

IBC’s 23rd Antibody Engineering and 10th Antibody Therapeutics Conferences and the Annual Meeting of The Antibody Society

Marquardt, John, Begent, Richard H.J., Chester, Kerry, Huston, James S., Bradbury, Andrew, Scott, Jamie K., Thorpe, Philip E., Veldman, Trudi, Reichert, Janice M., Weiner, Louis M.

Journal:

Year:

2012

Language:

english

File:

PDF, 400 KB

english, 2012

26

Successful management of metastatic and primary germ cell tumors in the brain

J. S. Gordon Rustin, Edward S. Newlands, Kenneth D. Bagshawe, H. J. RICHARD Begent, S. Michael Crawford

Journal:

Year:

1986

Language:

english

File:

PDF, 647 KB

english, 1986

27

The effect of second antibody clearance on the distribution and dosimetry of radiolabelled anti-cea antibody in a human colonic tumor xenograft model

R. Barbara Pedley, Roger Dale, Joan A. Boden, Richard H. J. Begent, Pat A. Keep, Alan J. Green

Journal:

International Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 651 KB

english, 1989

28

NCRI Informatics Initiative

Begent, Richard H.J., Kerr, Peter, Parkinson, Helen, Reddington, Fiona, Wilkinson, J. Max

Journal:

Nature Biotechnology

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

29

A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics

Daniel I. R. Spencer, Lynda Robson, Des Purdy, Nick R. Whitelegg, N. Paul Michael, Jeetendra Bhatia, Surinder K. Sharma, Anthony R. Rees, Nigel P. Minton, Richard H. J. Begent, Kerry A. Chester

Journal:

Year:

2002

Language:

english

File:

PDF, 855 KB

english, 2002

30

Engineering a Single-Chain Fv Antibody to αvβ6 Integrin Using the Specificity-Determining Loop of a Foot-and-Mouth Disease Virus

Heide Kogelberg, Berend Tolner, Gareth J. Thomas, Danielle Di Cara, Shane Minogue, Bala Ramesh, Serena Sodha, Dan Marsh, Mark W. Lowdell, Tim Meyer, Richard H.J. Begent, Ian Hart, John F. Marshall, Ke

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.63 MB

english, 2008

31

Liposomal clearance of antibodies to tumour products: Possible improvement of tumour detection

BARRATT, GILLIAN M., RYMAN, BRENDA E., BODEN, JOAN A., KEEP, PATRICIA A., SEARLE, FRANCES, BEGENT, RICHARD H., BAGSHAWE, KENNETH D.

Journal:

Biochemical Society Transactions

Year:

1981

Language:

english

File:

PDF, 312 KB

english, 1981

32

A single chain Fv derived from a filamentous phage library has distinct tumour targeting advantages over one derived from a hybridoma

Marlies J. Verhaar, Kerry A. Chester, Patricia A. Keep, Lynda Robson, R. Barbara Pedley, Joan A. Boden, Robert E. Hawkins, Richard H. J. Begent

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 498 KB

english, 1995

33

Deglycosylation to obtain stable and homogeneous Pichia pastoris-expressed N–A1 domains of carcinoembryonic antigen

Noelia Sainz-Pastor, Berend Tolner, Alexandra Huhalov, Heide Kogelberg, Yie Chia Lee, Delin Zhu, Richard Henry John Begent, Kerry Ann Chester

Journal:

International Journal of Biological Macromolecules

Year:

2006

Language:

english

File:

PDF, 463 KB

english, 2006

34

Liposomes as aids to tumour detection

BARRATT, GILLIAN M., RYMAN, BRENDA E., CHESTER, KERRY A., BEGENT, RICHARD H. J.

Journal:

Biochemical Society Transactions

Year:

1984

Language:

english

File:

PDF, 226 KB

english, 1984

35

Quantitation in 131 I-radioimmunotherapy using spect

Simon J. Riggs, Alan J. Green, Richard H. J. Begent, Kenneth D. Bagshawe

Journal:

International Journal of Cancer

Year:

1988

Language:

english

File:

PDF, 294 KB

english, 1988

36

Extended Glycoprotein Structure of the Seven Domains in Human Carcinoembryonic Antigen by X-ray and Neutron Solution Scattering and an Automated Curve Fitting Procedure: Implications for Cellular Adhesion

Mark K. Boehm, Olga M. Mayans, Jeremy D. Thornton, Richard H.J. Begent, Pat A. Keep, Stephen J. Perkins

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 704 KB

english, 1996

37

Production and tumour-binding characterization of a chimeric anti-CEA Fab expressed in Eschericwa coli

Kerry A. Chester, Lynda Robson, Patricia A. Keep, R. Barbara Pedlly, Joan A. Boden, Geoffrey M. Boxer, Robert E. Hawkins, Richard H. J. Begent

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 1.93 MB

english, 1994

38

Synergy between vascular targeting agents and antibody-directed therapy

R.Barbara Pedley, Ethaar El-Emir, Aiden A Flynn, Geoffrey M Boxer, Jason Dearling, James A Raleigh, Sally A Hill, Sam Stuart, Reeya Motha, Richard H.J Begent

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2002

Language:

english

File:

PDF, 345 KB

english, 2002

39

A novel technique, using radioluminography, for the measurement of uniformity of radiolabelled antibody distribution in a colorectal cancer xenograft model

Aiden A Flynn, Alan J Green, Geoffrey M Boxer, Joanne L Casey, R.Barbara Pedley, Richard H.J Begent

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1999

Language:

english

File:

PDF, 1.27 MB

english, 1999

40

Guidelines for information about therapy experiments: a proposal on best practice for recording experimental data on cancer therapy

Alejandra N González-Beltrán, May Y Yong, Gairin Dancey, Richard Begent

Journal:

BMC Research Notes

Year:

2012

Language:

english

File:

PDF, 961 KB

english, 2012

41

Localization of radiolabeled anti-CEA antibody in subcutaneous and intrahepatic colorectal xenografts: influence of tumor size and location within host organ on antibody uptake

Jason L.J. Dearling, Aiden A. Flynn, Uzma Qureshi, Stephen Whiting, Geoffrey M. Boxer, Alan Green, Richard H.J. Begent, R. Barbara Pedley

Journal:

Nuclear Medicine and Biology

Year:

2009

Language:

english

File:

PDF, 1008 KB

english, 2009

42

Accurate quantification of131I distribution by gamma camera imaging

Alan J. Green, Sarah E. Dewhurst, Richard H. J. Begent, Kenneth D. Bagshawe, Simon J. Riggs

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

1990

Language:

english

File:

PDF, 445 KB

english, 1990

43

In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein

N.Paul Michael, Kerry A. Chester, Roger G. Melton, Lynda Robson, William Nicholas, Joan A. Boden, R.Barbara Pedley, Richard H.J. Begent, Roger F. Sherwood, Nigel P. Minton

Journal:

Immunotechnology

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996

44

Improved radioimmunodetection of tumours using liposome-entrapped antibody

Barratt, Gillian M., Ryman, Brenda E., Begent, Richard H.J., Keep, Patricia A., Searle, Frances, Boden, Joan A., Bagshawe, Kenneth D.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1983

Language:

english

File:

PDF, 854 KB

english, 1983

45

8th International hammersmith meeting on advances in applications of monoclonal antibodies in clinical oncology, 8–13 May 1991

Chester, Kerry A., Begent, Richard H.J.

Journal:

European Journal of Cancer

Year:

1992

Language:

english

File:

PDF, 344 KB

english, 1992

46

Targeting Strategy for Gene Delivery to Carcinoembryonic Antigen-Producing Cancer Cells by Retrovirus Displaying a Single-Chain Variable Fragment Antibody

Konishi, Hiroyasu, Ochiya, Takahiro, Chester, Kerry A., Beǵent, Richard H. J., Muto, Tetsuichiro, Sugimura, Takashi, Terada, Masaaki

Journal:

Human Gene Therapy

Year:

1998

Language:

english

File:

PDF, 8.64 MB

english, 1998

47

Crystal structure of the anti-(carcinoembryonic antigen) single-chain Fv antibody MFE-23 and a model for antigen binding based on intermolecular contacts

BOEHM, Mark K., CORPER, Adam L., WAN, Tommy, SOHI, Maninder K., SUTTON, Brian J., THORNTON, Jeremy D., KEEP, Patricia A., CHESTER, Kerry A., BEGENT, Richard H.J., PERKINS, Stephen J.

Journal:

Biochemical Journal

Year:

2000

Language:

english

File:

PDF, 353 KB

english, 2000

48

Relationship between tumour morphology, antigen and antibody distribution measured by fusion of digital phosphor and photographic images

Aiden A. Flynn, Geoffrey M. Boxer, Richard H. J. Begent, R. Barbara Pedley

Journal:

Cancer Immunology, Immunotherapy

Year:

2001

Language:

english

File:

PDF, 218 KB

english, 2001

49

4861722 Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-lysine

Barratt, Gillian M., Ryman, Brenda E., Begent, Richard H.J., Keep, Patricia A., Searle, Frances, Boden, Joan A., Bagshawe, Kenneth D.

Journal:

Biotechnology Advances

Year:

1990

Language:

english

File:

PDF, 66 KB

english, 1990

50

Combined cytotoxic and progestogen therapy for advanced breast cancer

Robert D. Rubens, Richard H. J. Begent, Robert K. Knight, Sheila A. Sexton, John L. Hayward

Journal:

Year:

1978

Language:

english

File:

PDF, 453 KB

english, 1978

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